Description

Cbz-Phe-Arg-Oh is a protected tripeptide derivative featuring benzyloxycarbonyl (Cbz) and carboxylic acid termini. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic peptides and biochemical probes.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer, biologically active peptide sequences.
• Biochemical Research: Used as a standard or reagent in proteomics and enzyme substrate studies.
• Solid-Phase Peptide Synthesis (SPPS): An essential protected fragment for the sequential assembly of custom peptides.
• Drug Discovery: Employed in medicinal chemistry programs to create peptide-based drug candidates.
• Academic Research: Utilized in university and institutional labs for studying peptide structure and function.

Basic Information

Product Name	Cbz-Phe-Arg-Oh
CAS No.	32949-41-0
Molecular Formula	C27H36N6O5
Molecular Weight	524.61 g/mol
Synonyms	Nα-Carbobenzoxy-L-phenylalanyl-L-arginine; Z-Phe-Arg-OH; CBZ-Phenylalanine-Arginine; Benzyloxycarbonyl-Phe-Arg; N-Cbz-L-phenylalanyl-L-arginine; Z-F-R-OH; L-Phenylalanine, N-[(1S)-1-[[(1S)-4-amino-1-(carboxymethyl)butyl]amino]carbonyl]-2-phenylethyl]carbamic acid phenylmethyl ester
EINECS	Contact for details

Quality Control

Our Cbz-Phe-Arg-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	-20.0° to -25.0° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.