Description

Boc-Glu(Obzl)-Osu is a protected amino acid derivative widely used as a key building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the controlled incorporation of glutamic acid with orthogonal side-chain protection.
• Solution-Phase Peptide Synthesis: Used in the synthesis of peptide fragments and custom peptides in solution.
• Pharmaceutical Intermediate: Serves as a building block in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific labeling or modification of peptides and proteins.
• Biochemical Research: Employed in studying enzyme-substrate interactions and protein structure-function relationships.
• Combinatorial Chemistry: Used in libraries for drug discovery to create diverse peptide structures.

Basic Information

Product Name	Boc-Glu(Obzl)-Osu
CAS No.	32886-40-1
Molecular Formula	C₂₂H₂₈N₂O₈
Molecular Weight	448.47 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-glutamic acid 5-benzyl ester N-succinimidyl ester; Boc-L-glutamic acid 5-benzyl ester N-hydroxysuccinimide ester; Boc-Glu(OBzl)-OSu; N-Boc-L-glutamic acid γ-benzyl ester N-succinimidyl ester; Nα-Boc-L-glutamic acid 5-benzyl ester N-oxysuccinimide ester; (S)-5-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid 2,5-dioxopyrrolidin-1-yl ester; Boc-Glu-OBzl-OSu; Boc-L-Glu(OBzl)-OSu
EINECS	Contact for details

Quality Control

Our Boc-Glu(Obzl)-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation analysis, to confirm identity, purity, and chiral integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-15.0° to -18.0° (c=1 in DMF)
Melting Point	105°C - 110°C
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.