Description

6-Methylthio-9-Trimethylsilyl-9H-Purine is a key organosilicon-protected purine derivative, serving as a versatile and reactive synthetic intermediate. Its primary value lies in enabling precise chemical modifications to the purine scaffold, which is foundational to numerous biologically active compounds. This product is essential for researchers and manufacturers in pharmaceutical development, particularly in the synthesis of nucleoside analogs, antiviral agents, and other fine chemicals requiring selective functionalization.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside and nucleotide analogs with potential therapeutic activity.
• Antiviral Drug Research: Used in the development of prodrugs and modified nucleosides targeting viral polymerases.
• Agrochemical Synthesis: Intermediate for creating purine-based plant growth regulators or herbicides.
• Bioconjugation & Labeling: The trimethylsilyl group allows for further derivatization, useful in creating labeled probes or conjugates for biochemical studies.
• Material Science Research: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) incorporating nitrogen-rich heterocycles.
• Custom Synthesis & Process Development: Employed in route scouting and optimization for the commercial production of complex purine-containing molecules.

Basic Information

Item	Detail
Product Name	6-Methylthio-9-Trimethylsilyl-9H-Purine
CAS No.	32865-87-5
Molecular Formula	C9H16N4SSi
Molecular Weight	240.41 g/mol
Synonyms	9-Trimethylsilyl-6-methylthiopurine; 6-(Methylthio)-9-(trimethylsilyl)-9H-purine; 6-Methylmercapto-9-trimethylsilylpurine; Purine, 6-(methylthio)-9-(trimethylsilyl)-; TMS-6-methylthiopurine; N9-Trimethylsilyl-6-methylthiopurine; 6-Methylsulfanyl-9-trimethylsilyl-9H-purine
EINECS	Contact for details

Quality Control

Our 6-Methylthio-9-Trimethylsilyl-9H-Purine is produced under controlled conditions to ensure high chemical purity and lot-to-lot consistency, suitable for research and development applications. All batches undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.