Description

Dimethyl L-Cystinate Dihydrochloride is a high-purity, protected derivative of the amino acid L-cysteine, specifically designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring a stable, reactive building block for peptide synthesis and biochemical studies. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for developing novel therapeutic agents and conducting proteomics research.

Application

• Pharmaceutical Intermediate: Serves as a key protected precursor in the solid-phase and solution-phase synthesis of complex peptides and protein mimetics.
• Bioconjugation Reagent: Used for introducing disulfide bonds or thiol-reactive sites into biomolecules for drug delivery systems and diagnostic probes.
• Biochemical Research: Essential in studying protein folding, disulfide bridge formation, and redox biology in controlled laboratory settings.
• Protecting Group Strategy: The dimethyl ester and dihydrochloride salt provide enhanced stability for the cysteine thiol and amine functionalities during multi-step organic syntheses.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for method development and quality control of related compounds.

Basic Information

Product Name	Dimethyl L-Cystinate Dihydrochloride
CAS No.	32854-09-4
Molecular Formula	C5H12Cl2NO2S
Molecular Weight	221.12 g/mol
Synonyms	L-Cystine dimethyl ester dihydrochloride; Dimethyl (2R,2'R)-3,3'-disulfanediylbis(2-aminopropanoate) dihydrochloride; H-Cys(OMe)-OMe·2HCl; Methyl L-cystinate hydrochloride; Cystine dimethyl ester hydrochloride; (R,R)-Dimethyl 3,3'-dithiobis(2-aminopropanoate) dihydrochloride
EINECS	Contact for details

Quality Control

Our Dimethyl L-Cystinate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.