Description

n-[2-[(1,4-Dihydro-4-Oxoquinazolin)-2-Yl]Phenyl]-4-Methylbenzenesulfonamide is a high-purity, specialized organic compound belonging to the quinazolinone sulfonamide class. This chemical is valued for its role as a critical pharmaceutical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting specific enzymatic pathways.
• Research & Development (R&D): Used in medicinal chemistry for the discovery and optimization of new chemical entities with potential biological activity.
• API Synthesis: Serves as a precursor in the multi-step manufacturing process of final Active Pharmaceutical Ingredients.
• Biochemical Research: Employed in studies investigating enzyme inhibition and receptor-ligand interactions due to its specific structural motifs.
• Fine Chemical Production: Utilized in the production of other high-value, specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	n-[2-[(1,4-Dihydro-4-Oxoquinazolin)-2-Yl]Phenyl]-4-Methylbenzenesulfonamide
CAS No.	32787-68-1
Molecular Formula	C21H17N3O3S
Molecular Weight	391.44 g/mol
Synonyms	2-[(2-Tosylaminophenyl)quinazolin-4(1H)-one]; N-[2-(1,4-Dihydro-4-oxoquinazolin-2-yl)phenyl]-4-methylbenzenesulfonamide; 2-(2-Tosylaminophenyl)-1,4-dihydroquinazolin-4-one; TSAQ; Quinazolinone sulfonamide derivative; 32787-68-1; 2-(2-((4-Methylphenyl)sulfonamido)phenyl)-1,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our n-[2-[(1,4-Dihydro-4-Oxoquinazolin)-2-Yl]Phenyl]-4-Methylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.