Description

5-Bromo-2-Chloropyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable and scalable synthesis routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for creating functionalized polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce the pyrimidine core.
• Nucleoside Analog Development: Employed in the research and synthesis of modified nucleosides and nucleotides.
• Chemical Research & Development: A valuable reagent for exploring new heterocyclic chemistry and creating compound libraries for screening.

Basic Information

Product Name	5-Bromo-2-Chloropyrimidine
CAS No.	32779-36-5
Molecular Formula	C4H2BrClN2
Molecular Weight	193.43 g/mol
Synonyms	2-Chloro-5-bromopyrimidine; 5-Bromo-2-chloro-pyrimidine; Pyrimidine, 5-bromo-2-chloro-; 32779-36-5; 2-Chloro-5-bromopyrimidine; 5-Brom-2-chlorpyrimidin; 5-Bromo-2-chloro-1,3-diazine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.