Description

3-Methyl-5-(Trifluoromethyl)Pyrimido[5,4-E]-1,2,4-Triazin-7-Amine is a specialized heterocyclic organic compound featuring a fused pyrimidotriazine core, distinguished by the presence of a trifluoromethyl group which imparts unique physicochemical properties. This compound serves as a high-value advanced intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the agrochemical and life sciences sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting enzymes and receptors where the trifluoromethyl group enhances metabolic stability and binding affinity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure to create compounds with specific biological activity.
• Material Science Precursor: Serves as a starting material for synthesizing specialty chemicals, dyes, or ligands for catalytic systems in advanced material applications.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3-Methyl-5-(Trifluoromethyl)Pyrimido[5,4-E]-1,2,4-Triazin-7-Amine
CAS No.	32709-28-7
Molecular Formula	C8H5F3N6
Molecular Weight	242.16 g/mol
Synonyms	3-Methyl-5-(trifluoromethyl)-7H-pyrimido[5,4-e][1,2,4]triazin-7-amine; 7-Amino-3-methyl-5-(trifluoromethyl)pyrimido[5,4-e]-1,2,4-triazine; 32709-28-7; 3-Methyl-5-trifluoromethylpyrimido[5,4-e]-1,2,4-triazin-7-amine; 5-(Trifluoromethyl)-3-methylpyrimido[5,4-e][1,2,4]triazin-7-amine
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(Trifluoromethyl)Pyrimido[5,4-E]-1,2,4-Triazin-7-Amine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.