Description

n-Methyl-5-(Trifluoromethyl)Pyrimido[5,4-E]-1,2,4-Triazin-7-Amine CAS NO 32709-24-3 is a high-value, heterocyclic organic compound featuring a fused pyrimidotriazine core substituted with a trifluoromethyl group and a methylated amine. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides with enhanced activity.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Organic Synthesis: Employed as a specialized scaffold for constructing complex heterocyclic molecules in academic and industrial labs.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme mechanisms or biological pathways.

Basic Information

Product Name	n-Methyl-5-(Trifluoromethyl)Pyrimido[5,4-E]-1,2,4-Triazin-7-Amine
CAS No.	32709-24-3
Molecular Formula	C8H5F3N6
Molecular Weight	242.16 g/mol
Synonyms	7-Amino-5-(trifluoromethyl)-1-methylpyrimido[5,4-e][1,2,4]triazine; 5-(Trifluoromethyl)-1-methylpyrimido[5,4-e][1,2,4]triazin-7-amine; 1-Methyl-5-(trifluoromethyl)pyrimido[5,4-e][1,2,4]triazin-7-amine; n-Methyl-5-(trifluoromethyl)pyrimido[5,4-e]-1,2,4-triazin-7-amine; CAS 32709-24-3; 32709-24-3
EINECS	Contact for details

Quality Control

Our n-Methyl-5-(Trifluoromethyl)Pyrimido[5,4-E]-1,2,4-Triazin-7-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.