Description

2-Pyrimidineacetonitrile, 4,6-Dimethyl- (8Ci,9Ci) is a high-purity, heterocyclic nitrile building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the 4,6-dimethylpyrimidine moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the pyrimidine core is pharmacologically active.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that incorporate substituted pyrimidine structures for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis, leveraging the nitrile group for further functionalization.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers, where its aromatic system can contribute to charge transport.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes, taking advantage of its reactive nitrile group for bioconjugation.

Basic Information

Item	Details
Product Name	2-Pyrimidineacetonitrile, 4,6-Dimethyl- (8Ci,9Ci)
CAS No.	32691-58-0
Molecular Formula	C8H9N3
Molecular Weight	147.18 g/mol
Synonyms	4,6-Dimethyl-2-pyrimidineacetonitrile; (4,6-Dimethylpyrimidin-2-yl)acetonitrile; 2-(Cyanomethyl)-4,6-dimethylpyrimidine; 4,6-Dimethyl-2-pyrimidinylacetonitrile; 4,6-Dimethylpyrimidine-2-acetonitrile; α-(4,6-Dimethyl-2-pyrimidinyl)acetonitrile; NSC 163083
EINECS	Contact for details

Quality Control

Our 2-Pyrimidineacetonitrile, 4,6-Dimethyl- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.