Description

5,5’-Dihydroxylysinonorleucine is a specialized biochemical compound, a cross-linking amino acid derivative that plays a significant role in advanced research and development. Its primary value lies in its function as a biomarker and a key intermediate in studying collagen and elastin cross-linking, which is crucial for understanding connective tissue physiology and pathology. This makes it an essential material for researchers and developers in the pharmaceutical, biomedical research, and diagnostic sectors, particularly those focused on metabolic disorders, aging, and tissue engineering.

Application

• Biomedical Research: Critical as a biochemical standard and biomarker in studies of collagen and elastin metabolism, fibrosis, and connective tissue diseases.
• Diagnostic Development: Used in the development and calibration of assays (e.g., ELISA, LC-MS/MS) for quantifying cross-link compounds in biological fluids like urine and serum.
• Pharmaceutical R&D: Serves as a reference compound and intermediate in drug discovery programs targeting conditions such as scleroderma, liver cirrhosis, and cardiovascular stiffening.
• Nutraceutical & Cosmeceutical Research: Employed in studies investigating anti-aging compounds and formulations aimed at improving skin elasticity and reducing wrinkles.
• Academic Research: A vital tool in university and institutional labs for fundamental research in biochemistry, molecular biology, and pathology.
• Quality Control Standards: Used as a high-purity reference material in analytical laboratories to ensure accuracy in related biochemical testing.

Basic Information

Product Name	5,5’-Dihydroxylysinonorleucine
CAS No.	32619-23-1
Molecular Formula	C12H24N2O6
Molecular Weight	292.33 g/mol
Synonyms	5,5'-DHLNL; Dihydroxylysinonorleucine; Lysinonorleucine, 5,5'-dihydroxy-; (2S)-2-Amino-6-[[(2S)-2-amino-5-hydroxypentyl]amino]-5-hydroxyhexanoic acid; 5-Hydroxy-5'-hydroxylysinonorleucine; Collagen Cross-link; Elastin Cross-link Intermediate; Biomarker for Collagen Turnover
EINECS	Contact for details

Quality Control

Our 5,5’-Dihydroxylysinonorleucine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality standards, and our analytical methods, including HPLC and mass spectrometry, are validated to provide reliable data for our clients' critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.