Description

Ac-Leu-Nhme is a protected leucine derivative, specifically N-Acetyl-L-leucine methylamide, widely utilized as a key building block in peptide synthesis and pharmaceutical research. This compound is essential for constructing peptide chains with specific structural and functional properties, offering researchers precise control over molecular design. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers involved in developing novel therapeutic peptides and bioactive molecules.

Application

• Peptide Synthesis: A crucial intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the discovery and development of new peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a modified amino acid residue for creating labeled peptides or peptide-protein conjugates for diagnostic and research applications.
• Chemical Biology: Employed in studying protein-protein interactions and enzyme mechanisms by incorporating it into probe molecules.
• Fine Chemical Production: Acts as a chiral building block for the manufacture of more complex, non-peptide organic compounds requiring the leucine side chain motif.

Basic Information

Product Name	Ac-Leu-Nhme
CAS No.	32483-15-1
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	N-Acetyl-L-leucine methylamide; Acetyl-leucine methylamide; L-Leucine, N-acetyl-, methylamide; N-Acetyl-L-leucine N'-methylamide; Methyl N-acetyl-L-leucinamate; Ac-Leu-NHMe; Nα-Acetyl-L-leucinamide, N-methyl-
EINECS	Contact for details

Quality Control

Our Ac-Leu-Nhme is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.