Description

Vasopressin, 9-Des-Gly-NH(2)-Lys- is a synthetic analogue of the endogenous neurohypophysial hormone, vasopressin, specifically modified at the C-terminus. This modification is critical for research into receptor binding affinity, metabolic stability, and the development of novel therapeutic agents targeting vasopressin pathways. It is an essential high-purity reference standard and building block for pharmaceutical R&D, particularly in endocrinology and cardiovascular research. Key users include biopharmaceutical companies, contract research organizations (CROs), and academic institutions focused on peptide chemistry and drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualification and calibration of analytical methods (HPLC, MS) in quality control laboratories.
• Biochemical Research: Serves as a key reagent in studies investigating the structure-activity relationships (SAR) of vasopressin and its receptors (V1a, V1b, V2).
• Drug Discovery & Development: Acts as a precursor or intermediate in the synthesis of novel peptide-based therapeutics for conditions like diabetes insipidus, septic shock, and bleeding disorders.
• In-vitro Diagnostics (IVD): May be utilized in the development of immunoassays and test kits for measuring vasopressin levels in clinical samples.
• Academic Research: Fundamental tool for exploring the physiological and pathological roles of vasopressin in central nervous system and renal function.

Basic Information

Product Name	Vasopressin, 9-Des-Gly-NH(2)-Lys-
CAS No.	32472-43-8
Molecular Formula	C45H66N14O11S2
Molecular Weight	1027.2 g/mol
Synonyms	9-Desglycinamide-8-lysine-vasopressin; Desmopressin Impurity; [8-Lysine]-Vasopressin, 9-Des-Gly-NH2-; 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-4-L-arginine-8-L-lysine-vasopressin; DDAVP related compound; Lypressin analogue; 8-Lys-Vasopressin(1-8); Arg-Vasopressin, 9-Des-Gly-NH2, 8-Lys-
EINECS	Contact for details

Quality Control

Our Vasopressin, 9-Des-Gly-NH(2)-Lys- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity assays, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.