Description

α-Methyl-Dl-Histidine Dihydrochloride is a chemically modified derivative of the amino acid histidine, presented as its stable dihydrochloride salt. This compound is valued in biochemical and pharmaceutical research for its role as a potential enzyme inhibitor and a tool for studying histidine metabolism and related pathways. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in metabolic studies, proteomics, and the synthesis of specialized bioactive molecules.

Application

• Biochemical Research: Used as a reference standard or inhibitor in enzymatic studies related to histidine decarboxylase and other histidine-metabolizing enzymes.
• Pharmaceutical Intermediates: Serves as a key building block in the research and development of novel therapeutic agents and diagnostic compounds.
• Metabolic Pathway Analysis: Employed in laboratory settings to investigate histidine-related metabolic processes and their physiological implications.
• Proteomics & Peptide Synthesis: Acts as a modified amino acid precursor for the synthesis of specialized peptides and proteins for research purposes.
• Nutritional Science Studies: Utilized in research exploring amino acid analogs and their effects on biological systems.

Basic Information

Product Name	α-Methyl-Dl-Histidine Dihydrochloride
CAS No.	32381-18-3
Molecular Formula	C7H13N3O2 • 2HCl
Molecular Weight	260.12 g/mol
Synonyms	DL-α-Methylhistidine dihydrochloride; 1-Methyl-L-histidine dihydrochloride (racemic); (RS)-α-Methylhistidine dihydrochloride; 3-(1-Methyl-1H-imidazol-4-yl)-2-aminopropanoic acid dihydrochloride; L-Histidine, α-methyl-, dihydrochloride, DL-; α-Methylhistidine HCl; NSC 163044; 1-Methylhistidine dihydrochloride
EINECS	Contact for details

Quality Control

Our α-Methyl-Dl-Histidine Dihydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade research standards. A Certificate of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters is provided with every shipment to guarantee traceability and consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Optical Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.