Description

1-Fluoro-3-(Triethoxymethyl)Benzene is a specialized organofluorine building block featuring a reactive triethoxymethyl group. This compound matters for its dual functionality, serving as a key precursor in the synthesis of complex molecules where controlled introduction of a benzyl fluoride moiety is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to introduce fluorinated aromatic units into polymer backbones, altering properties like chemical resistance, thermal stability, and surface energy.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form biaryl structures.
• Protecting Group Chemistry: The triethoxymethyl group can be utilized as a protected form of an aldehyde or carboxylic acid derivative in multi-step synthetic sequences.

Basic Information

Product Name	1-Fluoro-3-(Triethoxymethyl)Benzene
CAS No.	32347-94-7
Molecular Formula	C13H19FO3
Molecular Weight	242.29 g/mol
Synonyms	3-Fluorobenzyl Alcohol Triethyl Ether; α,α,α-Triethoxy-3-fluorotoluene; (3-Fluorophenyl)methanol Triethyl Ether; 3-Fluorobenzyltriethyl Orthoformate; 1-Fluoro-3-(triethoxymethyl)benzene; m-Fluorobenzyl Alcohol Triethyl Ether; Benzene, 1-fluoro-3-(triethoxymethyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality control includes identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by chromatographic techniques (GC, HPLC). A Certificate of Analysis (COA) detailing specific results for each lot is available upon request, providing full traceability and supporting your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.