Description

(2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(Hydroxymethylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced biochemical research and pharmaceutical development. Its complex, stereochemically defined structure makes it a valuable building block for synthesizing specialized peptides and enzyme inhibitors. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise molecular tools for drug discovery and proteomics studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used as a specialized amino acid residue in solid-phase and solution-phase peptide synthesis to introduce unique structural and functional properties.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and protein function.
• Proteomics & Molecular Biology: Employed in the design and synthesis of activity-based probes (ABPs) and other tools for studying protein interactions and post-translational modifications.
• Fine Chemical Synthesis: Acts as a versatile chiral building block for the synthesis of complex natural product analogs and other high-value organic molecules.

Basic Information

Item	Detail
Product Name	(2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(Hydroxymethylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid
CAS No.	32260-87-0
Molecular Formula	C11H19N3O7S
Molecular Weight	337.35 g/mol
Synonyms	N2-[(Carboxymethyl)carbamoyl]-L-arginine; L-Arginine, N2-[(carboxymethyl)carbamoyl]-; (S)-2-Amino-5-[[(1R)-1-(carboxymethylcarbamoyl)-2-(hydroxymethylthio)ethyl]carbamoyl]pentanoic acid; Nω-Carbamoyl-Nδ-hydroxymethylthioethyl-L-ornithine derivative; Arg-CMHA; A specialized glutamine analog precursor
EINECS	Contact for details

Quality Control

Every batch of (2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(Hydroxymethylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, supporting compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.