Description

n-Decanoyl-Gly-Gly-L-Leu-Gly-OMe is a synthetic, protected tetrapeptide derivative featuring a C-terminal methyl ester and an N-terminal decanoyl (capric acid) chain. This molecular architecture makes it a valuable intermediate in peptide synthesis and pharmaceutical research, offering controlled lipophilicity and stability. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase or solution-phase synthesis of longer, biologically active peptide sequences for drug discovery.
• Biochemical Research: Used as a substrate or model compound in enzymatic studies, particularly for investigating protease specificity and kinetics.
• Prodrug Development: The lipophilic decanoyl group can be leveraged to enhance cell membrane permeability in the design of prodrug candidates.
• Cosmetic Peptide Synthesis: Acts as a precursor for synthesizing peptides with potential applications in cosmetic formulations for skin conditioning.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	n-Decanoyl-Gly-Gly-L-Leu-Gly-OMe
CAS No.	31944-48-6
Molecular Formula	C22H40N4O6
Molecular Weight	456.58 g/mol
Synonyms	Decanoyl-Gly-Gly-Leu-Gly-OMe; Caproyl-Gly-Gly-L-Leu-Gly-Methyl Ester; N-(1-Oxodecyl)glycylglycyl-L-leucylglycine Methyl Ester; Glycylglycyl-L-leucylglycine, N-decanoyl-, methyl ester; Methyl N-decanoylglycylglycyl-L-leucylglycinate
EINECS	Contact for details

Quality Control

Our n-Decanoyl-Gly-Gly-L-Leu-Gly-OMe is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.