Description

5-Methyl-L-Norleucine is a non-proteinogenic amino acid derivative of significant interest in advanced biochemical research and pharmaceutical development. This high-purity chiral building block is essential for the synthesis of peptides and peptidomimetics with enhanced metabolic stability and specific biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and bioactive compounds.
• Proteomics Research: Used as a stable isotope-labeled analog or a modified amino acid residue in metabolic pathway studies and protein structure-function analysis.
• Peptide Synthesis: Incorporated into custom peptides to alter physicochemical properties, such as hydrophobicity and conformational stability, for biological evaluation.
• Biochemical Tool Compound: Serves as a substrate or inhibitor in enzymatic studies to investigate amino acid metabolism and transport mechanisms.
• Nutraceutical Research: Explored for potential applications in specialized nutritional supplements and health products due to its unique structural properties.

Basic Information

Product Name	5-Methyl-L-Norleucine
CAS No.	31872-98-7
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	L-2-Aminoheptanoic acid; (S)-2-Aminoheptanoic acid; L-2-Amino-5-methylhexanoic acid; L-Homo-isoleucine; L-5-Methylnorleucine; (S)-5-Methylnorleucine; 5-Methyl-L-2-aminocaproic acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-L-Norleucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.