Description

Mexazolam is a high-purity benzodiazepine derivative, recognized for its specific pharmacological profile. This compound is of significant interest in the research and development of active pharmaceutical ingredients (APIs) and reference standards. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and fine chemical manufacturers engaged in the synthesis of specialized intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) in analytical chemistry for method development, validation, and quality control testing.
• Biochemical Research: Employed in preclinical studies to investigate the structure-activity relationships (SAR) of benzodiazepine receptors.
• Analytical Testing: Essential for calibrating equipment and ensuring accuracy in HPLC, GC-MS, and NMR analyses within quality control laboratories.
• Fine Chemical Synthesis: A valuable precursor for chemists developing novel compounds with potential therapeutic applications.

Basic Information

Product Name	Mexazolam
CAS No.	31868-18-5
Molecular Formula	C₁₈H₁₇ClN₂O₂
Molecular Weight	328.80 g/mol
Synonyms	10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one; CS-386; Melex; Mezazolam; Mexazolamum
EINECS	Contact for details

Quality Control

Our Mexazolam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.