Description

L-Homocysteine Thiolactone Hydrochloride is a key chiral building block and biochemical intermediate derived from the amino acid homocysteine. This compound is of significant interest for its role in research concerning homocysteine metabolism and associated cardiovascular and neurological conditions. It serves as a critical precursor in the synthesis of more complex molecules for pharmaceutical development and biochemical studies. Researchers and manufacturers in the life sciences and fine chemical sectors utilize this high-purity material for advanced applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting metabolic disorders and cardiovascular diseases.
• Biochemical Research: Used extensively in studies of homocysteine metabolism, oxidative stress, and the biochemical pathways related to atherosclerosis and neurodegenerative diseases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in clinical and research laboratories.
• Peptide Synthesis: Employed as a specialized building block for incorporating modified amino acid structures into peptides and peptidomimetics.
• Nutritional Science Studies: Utilized in research models to investigate the effects of homocysteine and its derivatives on cellular function and health outcomes.

Basic Information

Product Name	L-Homocysteine Thiolactone Hydrochloride
CAS No.	31828-68-9
Molecular Formula	C4H8ClNO2S
Molecular Weight	169.63 g/mol
Synonyms	(S)-2-Amino-4-butanolide Hydrochloride; L-2-Amino-4-butyrolactone Hydrochloride; L-Homocysteine Thiolactone HCl; (S)-3-Amino-dihydro-2(3H)-thiophenone Hydrochloride; Homocysteine Thiolactone Hydrochloride; HCTL HCl; L-Hcy TL HCl; 2-Amino-4-mercaptobutyric acid γ-lactone hydrochloride
EINECS	Contact for details

Quality Control

Our L-Homocysteine Thiolactone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.