Description

4-(2-Chloro-5-Fluoro-Pyrimidin-4-Yl)-Morpholine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecules in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential precursor for the synthesis of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	4-(2-Chloro-5-Fluoro-Pyrimidin-4-Yl)-Morpholine
CAS No.	31646-53-4
Molecular Formula	C8H9ClFN3O
Molecular Weight	217.63 g/mol
Synonyms	4-(2-Chloro-5-fluoropyrimidin-4-yl)morpholine; 2-Chloro-5-fluoro-4-morpholinopyrimidine; Morpholine, 4-(2-chloro-5-fluoro-4-pyrimidinyl)-; 4-(2-Chloro-5-fluoro-4-pyrimidinyl)morpholine; 4-(2-Chloro-5-fluoropyrimidin-4-yl)-morpholine; 31646-53-4; 2-Chloro-5-fluoro-4-(morpholin-4-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-5-Fluoro-Pyrimidin-4-Yl)-Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.