Description

Poly(1-Benzylhistidine) is a synthetic polypeptide derived from the amino acid histidine, where the imidazole nitrogen is protected by a benzyl group. This polymer is of significant interest in advanced biomaterials and pharmaceutical research due to its unique pH-responsive and self-assembling properties. It serves as a critical building block for researchers and manufacturers in the fields of drug delivery systems, tissue engineering, and smart polymeric materials.

Application

• Drug Delivery Systems: As a component in pH-sensitive micelles or nanoparticles for targeted and controlled release of therapeutic agents.
• Biomedical Research: Used in the study of polypeptide behavior, self-assembly mechanisms, and biomimetic materials.
• Polymer Chemistry: Serves as a model compound or a functional monomer for synthesizing novel copolymers with tailored properties.
• Tissue Engineering Scaffolds: Potential use in creating bioactive and responsive matrices for cell culture and tissue regeneration.
• Gene Delivery: Investigated as a non-viral vector component for complexing and delivering nucleic acids.
• Sensor Technology: Development of biosensors or diagnostic tools leveraging its conformational changes in response to environmental stimuli.

Basic Information

Product Name	Poly(1-Benzylhistidine)
CAS No.	31534-22-2
Molecular Formula	(C13H15N3O2)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(1-Benzyl-L-histidine); Poly(1-Bzl-His); PBLH; Poly(Nπ-benzyl-L-histidine); Poly(1-benzylimidazol-4-yl-methyl alanine); Poly(His(Bzl)); Poly(1-Benzylhistidine) homopolymer; Poly(Nim-benzylhistidine)
EINECS	Contact for details

Quality Control

Our Poly(1-Benzylhistidine) is produced under controlled conditions to ensure batch-to-batch consistency for research and development purposes. Each lot undergoes analysis to confirm identity, purity, and molecular weight characteristics. Certificates of Analysis (COA) detailing specific parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95% (Polymer Content)
Molecular Weight (GPC)	Specified range available (e.g., 5k-50k Da)
Residual Solvent	Meets ICH guidelines
Water Content	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.