Description

Tryptophyl Adenylate CAS NO 31528-64-0 is a specialized biochemical compound, an aminoacyl adenylate derivative of the essential amino acid tryptophan. This molecule is of significant interest in biochemical research and pharmaceutical development due to its role as a high-energy intermediate in protein biosynthesis. It serves as a critical substrate for studying enzymatic mechanisms, particularly those involving aminoacyl-tRNA synthetases. Key industries that utilize this compound include pharmaceutical R&D, academic research institutions, and biotechnology companies focused on metabolic pathway analysis and novel therapeutic discovery.

Application

• Biochemical Research: Used as a key intermediate in studies of aminoacyl-tRNA synthetase kinetics, specificity, and inhibition.
• Enzymology Studies: Serves as a high-energy substrate for investigating the mechanism of protein biosynthesis and fidelity of translation.
• Pharmaceutical Development: Employed in screening assays for the discovery of novel antibiotics that target bacterial protein synthesis machinery.
• Metabolic Pathway Analysis: Utilized as a tracer or standard in analytical methods to study tryptophan metabolism and related disorders.
• Academic & Institutional R&D: A fundamental reagent for graduate-level and post-doctoral research in molecular biology and biochemistry departments.
• Biotechnology: Applied in the development of cell-free protein synthesis systems and other in vitro translation platforms.

Basic Information

Product Name	Tryptophyl Adenylate
CAS No.	31528-64-0
Molecular Formula	C18H19N7O8P
Molecular Weight	492.36 g/mol
Synonyms	Tryptophan adenylate; Tryptophanyl adenylate; Tryptophan-AMP; L-Tryptophanyl adenylate; Adenosine 5'-(L-tryptophan) monophosphate; 5'-O-[N-(L-Tryptophanyl)sulfamoyl]adenosine; Tryptophan adenosine monophosphate; TRP-AMP
EINECS	Contact for details

Quality Control

Our Tryptophyl Adenylate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). We provide full traceability and documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.