Description

Pyrimidine, 4-Fluoro- (8Ci,9Ci) is a fluorinated heterocyclic aromatic compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom onto the pyrimidine core, which can dramatically alter the electronic properties, metabolic stability, and binding affinity of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including kinase inhibitors, antiviral agents, and anticancer compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators where fluorine substitution enhances bioactivity and environmental persistence.
• Material Science: Serves as a precursor for specialty chemicals, liquid crystals, and organic electronic materials.
• Biochemical Tool: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs engaged in custom fluorination chemistry and scale-up projects.

Basic Information

Product Name	Pyrimidine, 4-Fluoro- (8Ci,9Ci)
CAS No.	31462-55-2
Molecular Formula	C4H3FN2
Molecular Weight	98.08 g/mol
Synonyms	4-Fluoropyrimidine; 4-Fluoro-1,3-diazine; Fluoropyrimidine; 4-Fluoropyrimidine (8CI,9CI); 4-Fluoro-1,3-diazabenzene; NSC 5188; 1,3-Diazine, 4-fluoro-
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-Fluoro- (8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.