Description

2-Iodopyrimidine CAS NO 31462-54-1 is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, such as Suzuki and Sonogashira couplings, which are fundamental for constructing complex molecular architectures. This high-purity intermediate is critically needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and plant growth regulators through palladium-catalyzed cross-coupling.
• Material Science Research: Serves as a precursor for organic electronic materials, including ligands for OLEDs and molecular wires.
• Chemical Biology & Proteomics: Employed in tagging and bioconjugation strategies to modify biomolecules for study and diagnostics.
• Academic & Contract Research: A fundamental reagent in medicinal chemistry and methodology development laboratories worldwide.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated pyrimidine-based ligands for transition metal catalysts.

Basic Information

Product Name	2-Iodopyrimidine
CAS No.	31462-54-1
Molecular Formula	C4H3IN2
Molecular Weight	221.98 g/mol
Synonyms	Pyrimidine, 2-iodo-; 2-Iodopyrimidine; Iodopyrimidine; 2-Pyrimidinyl iodide; 2-Iodo-1,3-diazine; 31462-54-1; NSC 403914
EINECS	Contact for details

Quality Control

Our 2-Iodopyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.