Description

7-Chloro-4-Quinazolinol is a high-purity quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinazoline-based drug candidates, particularly those targeting kinase inhibition for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials and advanced polymers.
• Academic & R&D: Essential for methodological studies in organic chemistry and medicinal chemistry for constructing fused heterocyclic systems.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in chemical manufacturing.

Basic Information

Product Name	7-Chloro-4-Quinazolinol
CAS No.	31374-18-2
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	7-Chloro-4-hydroxyquinazoline; 4-Hydroxy-7-chloroquinazoline; 7-Chloro-4(1H)-quinazolinone; 7-Chloroquinazolin-4-ol; 7-Chloro-4-quinazolinone; 31374-18-2; 7-Chloro-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Quinazolinol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.