Description

4-Methylene-L-Glutamine is a specialized amino acid derivative with a unique reactive methylene group. This compound serves as a valuable building block and intermediate in advanced organic synthesis and biochemical research. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for developing novel compounds and studying metabolic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Biochemical Research: Used as a specialized substrate or analog in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Serves as a modified glutamine residue for introducing unique properties or reactive sites into synthetic peptides.
• Proteomics & Labeling: Potential use in chemical biology for protein labeling or as a probe due to its reactive methylene functionality.
• Fine Chemical Production: Intermediate for manufacturing complex, high-value specialty chemicals and chiral compounds.
• Academic Research: Tool compound for studying plant biochemistry (as a glutamine analog) and specialized organic reactions.

Basic Information

Product Name	4-Methylene-L-Glutamine
CAS No.	31138-12-2
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	L-4-Methyleneglutamine; (2S)-2-Amino-4-methylidene-4-carbamoylbutanoic acid; γ-Methyleneglutamine; 4-Methylene-L-glutamine; NSC 163049; 4-Methyleneglutamine; Glutamine, 4-methylene-
EINECS	Contact for details

Quality Control

Our 4-Methylene-L-Glutamine is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is assured through rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Chiral Purity	≥ 99.0% (L-isomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.