Description

2-Chloro-4-(N,N-Dimethylamino)pyrimidine is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis. Its core value lies in its reactive chloro and dimethylamino substituents, which enable precise functionalization for creating complex molecular architectures. This intermediate is critically needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based probes for target identification.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific pyrimidine-based scaffolds.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions.

Basic Information

Product Name	2-Chloro-4-(N,N-Dimethylamino)pyrimidine
CAS No.	31058-81-8
Molecular Formula	C6H9ClN3
Molecular Weight	158.61 g/mol
Synonyms	4-(Dimethylamino)-2-chloropyrimidine; 2-Chloro-4-(dimethylamino)pyrimidine; 2-Chloro-4-dimethylaminopyrimidine; 4-Dimethylamino-2-chloropyrimidine; N,N-Dimethyl-2-chloropyrimidin-4-amine; 31058-81-8; Pyrimidine, 2-chloro-4-(dimethylamino)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(N,N-Dimethylamino)pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.