Description

6-Ethyl-2,4,7-Tris(trimethylsilyloxy)pteridine is a specialized organosilicon derivative of the pteridine heterocycle, a core structure of significant biochemical interest. This compound matters as a key synthetic intermediate and protecting group reagent, offering enhanced solubility and stability for advanced organic synthesis. It is primarily needed by research institutions and pharmaceutical developers working on nucleotide analogs, enzyme inhibitors, and novel fluorophores for diagnostic applications.

Application

• Pharmaceutical Intermediate: Serves as a protected precursor in the synthesis of novel pteridine-based drug candidates, including potential antifolate agents and kinase inhibitors.
• Nucleotide Chemistry: Used in the modification and protection of nucleosides and nucleotides for medicinal chemistry and biochemical research.
• Fluorescent Probe Development: Acts as a building block for creating advanced fluorescent dyes and markers due to the inherent photophysical properties of the pteridine core.
• Material Science Research: Employed in the development of organic electronic materials and molecular sensors where specific electron-accepting or donating properties are required.
• Chemical Biology Tool: Utilized as a tagged molecular probe to study enzyme mechanisms and biomolecular interactions.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in heterocyclic and organosilicon chemistry.

Basic Information

Product Name	6-Ethyl-2,4,7-Tris(trimethylsilyloxy)pteridine
CAS No.	31053-51-7
Molecular Formula	C₁₇H₃₄N₄O₃Si₃
Molecular Weight	430.73 g/mol
Synonyms	2,4,7-Tris(trimethylsilyloxy)-6-ethylpteridine; 6-Ethyl-2,4,7-tris[(trimethylsilyl)oxy]pteridine; 6-Ethyl-2,4,7-tris(trimethylsiloxy)pteridine; Pteridine, 6-ethyl-2,4,7-tris[(trimethylsilyl)oxy]-; 6-Ethyl-2,4,7-tris-O-(trimethylsilyl)pteridine
EINECS	Contact for details

Quality Control

Our 6-Ethyl-2,4,7-Tris(trimethylsilyloxy)pteridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development purposes. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.