Description

(-)-Benzhexol Hydrochloride is the levorotatory enantiomer of the anticholinergic agent trihexyphenidyl hydrochloride. This specific stereoisomer is of significant interest in advanced pharmaceutical research and development due to its potential for targeted pharmacological activity and reduced side-effect profiles. It is primarily utilized by pharmaceutical companies and research institutions engaged in the synthesis of chiral drugs, neurological disorder research, and the development of novel therapeutic agents.

Application

• Active Pharmaceutical Ingredient (API) intermediate for chiral drug synthesis.
• Neurological Research, particularly in studies related to Parkinson's disease and extrapyramidal symptoms.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Preclinical Studies investigating the efficacy and pharmacokinetics of enantiomerically pure anticholinergics.
• Process Chemistry for the development and scale-up of stereoselective manufacturing routes.

Basic Information

Product Name	(-)-Benzhexol Hydrochloride
CAS No.	30953-85-6
Molecular Formula	C20H31NO•HCl
Molecular Weight	337.93 g/mol
Synonyms	(-)-Trihexyphenidyl Hydrochloride; (3R)-1-Cyclohexyl-1-phenyl-3-(1-piperidinyl)-1-propanol Hydrochloride; Levo-Trihexyphenidyl HCl; (R)-Trihexyphenidyl Hydrochloride; L-Trihexyphenidyl Hydrochloride; Benzhexol Hydrochloride (-)-form; Artane (enantiomer)
EINECS	Contact for details

Quality Control

Our (-)-Benzhexol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing parameters such as chiral purity, assay, and related substances. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.