Description

Oxytocin, Deamino-6-Carba- is a potent synthetic analogue of the endogenous neuropeptide hormone oxytocin, characterized by its enhanced metabolic stability and receptor selectivity. This modification, which replaces the disulfide bridge with a carbamethylene group, makes it a critical research tool for studying oxytocinergic pathways and developing novel therapeutic agents. It is essential for pharmaceutical R&D, academic research in neuroendocrinology, and the development of treatments for conditions related to social behavior, lactation, and uterine function.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control of related peptide therapeutics.
• Biomedical Research: A key reagent for investigating the structure-activity relationship (SAR) of oxytocin analogues and their interaction with the oxytocin receptor (OXTR).
• Drug Discovery & Development: Serves as a lead compound or intermediate in the development of next-generation therapeutics for psychiatric disorders (e.g., autism, anxiety, depression) and obstetric applications.
• Neuroendocrine Studies: Employed in in vitro and in vivo models to study the physiological and behavioral effects of oxytocin signaling, including social bonding, stress response, and maternal behavior.
• Biochemical Assays: Used in receptor binding assays, functional cell-based assays, and high-throughput screening (HTS) campaigns to identify new modulators of the oxytocin pathway.

Basic Information

Product Name	Oxytocin, Deamino-6-Carba-
CAS No.	30927-32-3
Molecular Formula	C₄₅H₆₆N₁₂O₁₂S₂
Molecular Weight	1003.2 g/mol
Synonyms	Carbetocin Impurity A; Deamino-6-Carba-Oxytocin; 1-[(4R,7S,10S,13S,16R,19R)-10-(2-Amino-2-oxoethyl)-19-[(2-amino-2-oxoethyl)carbamoyl]-7,13-bis(carbamoylmethyl)-16-(3-quanidinopropyl)-4-(hydroxymethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-6,9,12,15,18-pentaone]; Atosiban Related Compound A; 1-Deamino-6-Carba-Oxytocin; Tocatiban Impurity A; (Mpa¹,β-Ala⁸)-Oxytocin; 6-Carba-Deamino-Oxytocin
EINECS	Contact for details

Quality Control

Our Oxytocin, Deamino-6-Carba- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.