Description

n-[n-[(2R)-1-Oxo-2-Hydroxypentyl]-L-Pro-L-Ile-n-Methyl-L-Val-n-Methyl-L-Ala-]-β-Alanine Lactone CAS NO 30845-05-7 is a complex, cyclic peptide derivative with a defined stereochemistry. This compound is valued for its role as a key synthetic intermediate or reference standard in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors working on novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex peptide-based drug candidates.
• Research & Development: Used as a reference standard or starting material in medicinal chemistry programs targeting new therapeutic modalities.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of specialized peptide fragments.
• Bioconjugation Studies: Potential use in developing peptide-drug conjugates or other bioconjugates due to its reactive lactone and hydroxyl functionalities.
• Academic Research: Utilized in university and institutional labs for studying peptide synthesis, cyclization techniques, and structure-activity relationships (SAR).

Basic Information

Product Name	n-[n-[(2R)-1-Oxo-2-Hydroxypentyl]-L-Pro-L-Ile-n-Methyl-L-Val-n-Methyl-L-Ala-]-β-Alanine Lactone
CAS No.	30845-05-7
Molecular Formula	C28H48N6O7
Molecular Weight	580.72 g/mol
Synonyms	Cyclo(-L-Pro-L-Ile-N-Me-L-Val-N-Me-L-Ala-β-Ala-); (2R)-2-Hydroxypentanoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl-N-methyl-L-alanyl-β-alanine lactone; L-Pro-L-Ile-N-Me-L-Val-N-Me-L-Ala-β-Ala Lactone; Pentapeptide Lactone Derivative; Cyclic Pentapeptide Analog; 30845-05-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our n-[n-[(2R)-1-Oxo-2-Hydroxypentyl]-L-Pro-L-Ile-n-Methyl-L-Val-n-Methyl-L-Ala-]-β-Alanine Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.