Description

Poly-D-Glutamic Acid Sodium Salt is a high-purity, synthetic polyamino acid derivative. This compound is valued for its unique chiral structure, biodegradability, and anionic polyelectrolyte properties, offering distinct advantages over its L-isomer counterpart in specific applications. It serves as a critical material for advanced research and development in the pharmaceutical, biomedical, and cosmetic industries, where precise stereochemistry and material consistency are paramount.

Application

• Pharmaceutical Research & Drug Delivery: As a biocompatible and biodegradable polymer for constructing drug carriers, hydrogels, and sustained-release systems, leveraging its chiral specificity.
• Biomedical Materials: Used in the development of tissue engineering scaffolds, wound dressings, and surgical adhesives due to its non-immunogenic and absorbable nature.
• Cosmetic Science: Functions as a high-performance humectant, film-forming agent, and texture enhancer in advanced skincare formulations.
• Biochemical & Enzymology Studies: Serves as a chiral substrate or inhibitor in enzymatic assays and studies of glutamic acid metabolism and related pathways.
• Industrial Biotechnology: Potential applications in the production of specialty chemicals and as a flocculant or dispersant in environmentally sensitive processes.

Basic Information

Product Name	Poly-D-Glutamic Acid Sodium Salt
CAS No.	30811-79-1
Molecular Formula	(C5H7NO4Na)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(D-glutamic acid) sodium salt; Sodium Poly(D-glutamate); D-Polyglutamic Acid Sodium Salt; PGA (D-isomer) Sodium Salt; PDGA-Na; (D)-PGA-Na; Poly-α-D-glutamic acid sodium salt; Sodium poly(α-D-glutamate)
EINECS	Contact for details

Quality Control

Our Poly-D-Glutamic Acid Sodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including determination of molecular weight distribution, optical purity (enantiomeric excess), and residual solvent analysis, to ensure it meets the stringent requirements for research and commercial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and key physical-chemical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder or fibrous solid
Identification (IR)	Conforms to reference spectrum
Assay (on dried basis)	≥ 95.0% (as Sodium Poly-D-Glutamate)
Optical Rotation [α]D20	Specific range available per grade
Molecular Weight (Average)	Customizable (e.g., 5kDa - 500kDa)
Loss on Drying	≤ 8.0 %
Residue on Ignition (Sulfated Ash)	15.0 - 25.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Microbial Limits	Meets standard bioburden requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.