Description

Metildigoxin is a potent cardiac glycoside derivative, a semi-synthetic analog of digoxin, known for its enhanced bioavailability and predictable pharmacokinetic profile. This compound is critical for the development and formulation of specialized cardiovascular medications. It is primarily required by pharmaceutical manufacturers and advanced research institutions focused on cardiology and drug discovery.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of cardiac medications for treating heart failure and certain arrhythmias.
• Reference Standard for analytical testing, quality control, and method validation in pharmaceutical laboratories.
• Biochemical Research for studying the mechanism of action of cardiac glycosides on the Na+/K+-ATPase pump.
• Formulation Development for creating new dosage forms with improved therapeutic efficacy and patient compliance.
• Metabolite Studies in pharmacokinetic and pharmacodynamic research to understand drug metabolism pathways.

Basic Information

Product Name	Metildigoxin
CAS No.	30685-43-9
Molecular Formula	C₄₂H₆₆O₁₄
Molecular Weight	794.97 g/mol
Synonyms	Medigoxin; β-Methyldigoxin; Lanitop; Digicor; Metildigoxina; Methyl Digoxin; 3β-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide 3-methyl ether
EINECS	Contact for details

Quality Control

Our Metildigoxin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.