Description

Secretin, β-Asp(3)- CAS NO 30632-15-6 is a synthetic analogue of the gastrointestinal peptide hormone secretin, specifically modified at the third amino acid position with a β-aspartic acid residue. This engineered peptide is critical for advanced research and development in endocrinology and metabolic studies due to its enhanced stability and specific receptor binding profile. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on pancreatic function, digestive disorders, and peptide-based therapeutic discovery.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active ingredient in preclinical studies for novel gastrointestinal and metabolic therapies.
• Diagnostic Assay Development: Serves as a critical component in the calibration and validation of immunoassays and test kits for pancreatic exocrine function (e.g., secretin stimulation tests).
• Biochemical & Physiological Studies: Employed in laboratory investigations to study secretin receptor (SCTR) signaling, cAMP pathway activation, and bicarbonate secretion mechanisms.
• Academic & Clinical Research: Essential for university and hospital labs conducting research on digestive hormones, pancreatitis, cystic fibrosis, and related metabolic pathways.
• Peptide Chemistry & Analogue Synthesis: Acts as a key intermediate or target molecule for developing new peptide analogues with improved pharmacokinetic properties.

Basic Information

Product Name	Secretin, β-Asp(3)- CAS NO 30632-15-6
CAS No.	30632-15-6
Molecular Formula	C130H220N44O41
Molecular Weight	3055.4 g/mol
Synonyms	β-Asp(3)-Secretin; [β-Asp3]-Secretin; Secretin (human) (β-Asp3); H-His-Ser-Asp(β)-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2; Synthetic Secretin Analogue; Gastrointestinal Peptide Hormone Analogue
EINECS	Contact for details

Quality Control

Our Secretin, β-Asp(3)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, peptide content, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assayed; report with COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.