Description

2-Hydroxy-3-(3H-Imidazol-4-Yl)Propanoic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a unique imidazole side chain. This compound is a critical chiral building block and intermediate in the synthesis of complex bioactive molecules, offering significant value in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of histidine analogs, enzyme inhibitors, and potential active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies and enzyme-substrate interaction research.
• Peptide Synthesis: Incorporated into custom peptides to introduce imidazole functionality, which can act as a ligand for metal ions or participate in catalytic activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Academic & Discovery Chemistry: A valuable reagent for medicinal chemistry programs and the development of new chemical entities in university and industrial labs.

Basic Information

Product Name	2-Hydroxy-3-(3H-Imidazol-4-Yl)Propanoic Acid
CAS No.	30581-88-5
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	L-Ergothioneine Precursor; 3-(1H-Imidazol-4-yl)-2-hydroxypropanoic Acid; 2-Hydroxy-3-(1H-imidazol-5-yl)propanoic Acid; (2S)-2-Hydroxy-3-(1H-imidazol-4-yl)propanoic Acid; 4-Imidazolepropanoic acid, 2-hydroxy-; Histidinol carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-(3H-Imidazol-4-Yl)Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.