Description

Hydroxyallysine is a specialized amino acid derivative with a reactive allylic hydroxyl group, serving as a crucial intermediate in advanced organic synthesis and biochemical research. Its unique bifunctional structure makes it a valuable building block for constructing complex molecules, particularly in pharmaceutical development and peptide chemistry. This compound is essential for researchers and manufacturers in the life sciences, fine chemical, and advanced material sectors seeking to introduce specific functional handles into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs, particularly those targeting specific biological pathways.
• Peptide Modification & Conjugation: Used to introduce allylic or hydroxyl-functionalized side chains into peptides, enabling site-specific labeling, cross-linking, or PEGylation for drug delivery systems.
• Bioconjugation Chemistry: Serves as a versatile linker molecule for attaching drugs, dyes, or other payloads to antibodies, proteins, or nanoparticles in bioconjugate development.
• Cross-linking Agent: Utilized in polymer and material science to create cross-linked networks or hydrogels with tailored mechanical and chemical properties.
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of chemical probes for studying enzyme mechanisms, protein-protein interactions, and cellular processes.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Product Name	Hydroxyallysine
CAS No.	30382-02-6
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	2-Amino-5-(hydroxymethyl)-5-hexenoic acid; (2S)-2-Amino-5-(hydroxymethyl)-5-hexenoic acid; L-Hydroxyallysine; 5-(Hydroxymethyl)-5-hexenoic acid, 2-amino-; Hyl; Hydroxyallylglycine; 5-Hydroxymethyl-2,5-dihydro-2-furancarboxylic acid, 2-amino- (related forms).
EINECS	Contact for details

Quality Control

Our Hydroxyallysine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity assessment and chiral analysis to confirm enantiomeric integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting specifications for identity, purity, and related substances. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.