Description

N,N'-Dimethylarginine is a dimethylated derivative of the amino acid L-arginine, playing a significant role in nitric oxide synthase (NOS) regulation. This compound matters as a key endogenous inhibitor of NOS, making it a valuable research tool for studying cardiovascular function, endothelial health, and metabolic pathways. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors for developing diagnostic assays and investigating disease mechanisms.

Application

• Biomedical Research: Used as a critical standard and inhibitor in studies of nitric oxide (NO) metabolism, endothelial dysfunction, and cardiovascular diseases.
• Diagnostic Reagent Manufacturing: Serves as a key component in the production of ELISA kits and other diagnostic assays for measuring asymmetric dimethylarginine (ADMA) levels, a biomarker for cardiovascular risk.
• Pharmaceutical Development: Employed in preclinical research for drug discovery programs targeting conditions related to NO imbalance, such as hypertension, atherosclerosis, and renal failure.
• Biochemical Synthesis: Acts as a specialized building block or intermediate in the synthesis of more complex peptides and biochemical probes.
• Academic Research: Utilized in university and institutional labs for fundamental studies in biochemistry, cell signaling, and molecular biology.

Basic Information

Product Name	N,N'-Dimethylarginine
CAS No.	30344-00-4
Molecular Formula	C8H18N4O2
Molecular Weight	202.26 g/mol
Synonyms	NG,NG-Dimethylarginine; Asymmetric Dimethylarginine (ADMA); NG,NG-Dimethyl-L-arginine; L-NG,NG-Dimethylarginine; (2S)-2-Amino-5-[(amino-dimethylaminomethylene)amino]pentanoic acid; ADMA; SDMA (Note: Often refers to symmetric isomer); H-Arg(Me2)-OH
EINECS	Contact for details

Quality Control

Our N,N'-Dimethylarginine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.