Description

N,n-Dimethylarginine is a dimethylated derivative of the amino acid L-arginine, playing a significant role in nitric oxide synthase (NOS) regulation. This compound is valued as a critical biochemical tool and reference standard for research into cardiovascular function, endothelial health, and metabolic pathways. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors for developing diagnostic assays and investigating disease mechanisms.

Application

• Biochemical Research: Used as a reference standard and inhibitor in studies of nitric oxide (NO) metabolism and endothelial function.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and quality control of cardiovascular and metabolic drugs.
• Diagnostic Kit Manufacturing: Employed as a calibrator or component in ELISA and other immunoassay kits for measuring asymmetric dimethylarginine (ADMA) levels, a biomarker for cardiovascular risk.
• Academic Research: Utilized in university and institutional labs for fundamental research on cell signaling, aging, and renal function.
• Metabolomics Studies: Acts as a defined metabolite in profiling studies to understand disease states and metabolic disorders.

Basic Information

Product Name	N,n-Dimethylarginine
CAS No.	30315-93-6
Molecular Formula	C8H18N4O2
Molecular Weight	202.26 g/mol
Synonyms	Asymmetric Dimethylarginine (ADMA); NG,NG-Dimethylarginine; N(G),N(G)-Dimethyl-L-arginine; L-NG,NG-Dimethylarginine; Dimethylarginine; SDMA (Symmetric isomer); H-Arg(Me2)-OH; (2S)-2-Amino-5-[(amino-dimethylaminomethylene)amino]pentanoic acid
EINECS	Contact for details

Quality Control

Our N,n-Dimethylarginine is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high purity and consistency, suitable for sensitive research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles via HPLC, NMR, and MS is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.