Description

7-(Dimethylamino)-1,3-Dihydro-5-Phenyl-2H-1,4-Benzodiazepine-2-One is a high-purity benzodiazepine derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile pharmaceutical intermediate and a critical building block for research into central nervous system (CNS) active agents. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and fine chemical sectors for developing new therapeutic candidates and reference standards.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel benzodiazepine-based drug candidates targeting neurological and psychiatric disorders.
• Research & Development: Used as a key reference standard and building block in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial precursor in multi-step synthetic routes for complex active molecules.
• Biochemical Research: Employed in studies investigating the mechanism of action of benzodiazepines at GABA-A receptors.
• Fine Chemical Manufacturing: Utilized in the production of specialty chemicals and advanced materials requiring this specific heterocyclic structure.
• Analytical Standard: Provides a high-purity standard for quality control (QC) and analytical method development in pharmaceutical analysis.

Basic Information

Product Name	7-(Dimethylamino)-1,3-Dihydro-5-Phenyl-2H-1,4-Benzodiazepine-2-One
CAS No.	30144-56-0
Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34 g/mol
Synonyms	7-(Dimethylamino)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-Phenyl-7-(dimethylamino)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Dimethylamino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-(N,N-Dimethylamino)-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one; DMAPB; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 7-(Dimethylamino)-1,3-Dihydro-5-Phenyl-2H-1,4-Benzodiazepine-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.