Description

2,4-Diamino-5-(3,4-Dichlorobenzyl)Pyrimidine is a high-purity, heterocyclic organic compound that serves as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of dihydrofolate reductase (DHFR) inhibitors. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality intermediates for their synthesis processes.

Application

• Pharmaceutical Intermediate: Primary use as a key precursor in the synthesis of diaminopyrimidine-based drugs, including specific antimicrobial and antiparasitic agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its pyrimidine core structure.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in custom synthesis and contract manufacturing.
• Biochemical Research: Utilized in academic and industrial laboratories for studying enzyme inhibition, particularly related to folate metabolism pathways.
• Material Science: Potential application in the development of specialty chemicals and functional materials due to its aromatic and heterocyclic properties.

Basic Information

Product Name	2,4-Diamino-5-(3,4-Dichlorobenzyl)Pyrimidine
CAS No.	30077-58-8
Molecular Formula	C11H10Cl2N4
Molecular Weight	269.13 g/mol
Synonyms	5-[(3,4-Dichlorophenyl)methyl]-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4-dichlorobenzyl)pyrimidine; 5-(3,4-Dichlorobenzyl)-2,4-diaminopyrimidine; 2,4-Pyrimidinediamine, 5-[(3,4-dichlorophenyl)methyl]-; NSC 329860; Diaminopyrimidine derivative; DDAP; 3,4-Dichlorobenzylpyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 2,4-Diamino-5-(3,4-Dichlorobenzyl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and meet stringent impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and residual solvent levels is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.