Description

Insulin Chain B, Oxidized is a defined peptide fragment derived from the B-chain of insulin, specifically in its oxidized (disulfide) form. This high-purity biochemical is critical for research and development in the life sciences, serving as a precise reference standard and a key intermediate. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on diabetes research, metabolic studies, and peptide synthesis.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in insulin and biosimilar development.
• Biochemical Research: Serves as a critical reagent in studies of insulin structure, function, folding, and receptor binding mechanisms.
• Diagnostic Kit Development: Employed in the production and quality control of immunoassays and test kits for diabetes monitoring.
• Peptide Synthesis & Conjugation: Acts as a building block or precursor for the chemical synthesis of novel insulin analogs or peptide conjugates.
• Metabolic Pathway Studies: Utilized in in vitro and ex vivo research to investigate insulin signaling and related metabolic disorders.
• Quality Control & Compliance Testing: Essential for ensuring batch-to-batch consistency and regulatory compliance in insulin-related manufacturing processes.

Basic Information

Product Name	Insulin Chain B, Oxidized
CAS No.	30003-72-6
Molecular Formula	C157H232N40O47S2
Molecular Weight	3495.9 g/mol
Synonyms	Insulin B Chain (Oxidized); B-Chain of Insulin (Oxidized); Oxidized Insulin B-Chain; Insulin B-Chain Disulfide; [1-30]-Insulin B Chain; H-Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-OH (Disulfide bridge: Cys7-Cys19); Porcine Insulin B Chain (Oxidized)
EINECS	Contact for details

Quality Control

Our Insulin Chain B, Oxidized is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards. We support cGMP and ISO 9001 aligned practices for consistent, reliable supply.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.