Description

4-Chloro-5-Iodopyrimidin-2-Amine is a halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, enabling key structural modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: Serves as a versatile scaffold for cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex functionalities.
• Material Science: Building block for creating specialized polymers and organic electronic materials.
• Bioconjugation & Probe Development: Useful for labeling biomolecules or creating fluorescent probes due to its reactive halogen sites.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Chloro-5-Iodopyrimidin-2-Amine
CAS No.	3993-80-4
Molecular Formula	C4H3ClIN3
Molecular Weight	255.44 g/mol
Synonyms	2-Amino-4-chloro-5-iodopyrimidine; 5-Iodo-4-chloropyrimidin-2-amine; 4-Chloro-5-iodo-2-pyrimidinamine; 4-Chloro-5-iodo-2-aminopyrimidine; 3993-80-4; 4-Chloro-5-iodopyrimidin-2-ylamine; 2-Pyrimidinamine, 4-chloro-5-iodo-
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Iodopyrimidin-2-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.