Description

2-Amino-4-Chloropyrimidine CAS NO 3993-78-0 is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a chloro substituent, makes it a valuable scaffold for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Used in cross-coupling reactions, nucleophilic substitutions, and as a ligand precursor in coordination chemistry.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Dye & Pigment Manufacturing: Intermediate for producing heterocyclic dyes and colorants.

Basic Information

Product Name	2-Amino-4-Chloropyrimidine
CAS No.	3993-78-0
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	4-Chloro-2-pyrimidinamine; 4-Chloropyrimidin-2-amine; 2-Pyrimidinamine, 4-chloro-; 4-Chloro-2-aminopyrimidine; 2-Amino-4-chloropyrimidine; ACP; 3993-78-0
EINECS	223-649-7

Quality Control

Our 2-Amino-4-Chloropyrimidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.