Description

5-Methylorotic Acid is a specialized pyrimidine derivative and a key intermediate in nucleotide biosynthesis pathways. This high-purity compound is critical for research and development in advanced pharmaceutical synthesis and biochemical studies. It is primarily utilized by researchers in medicinal chemistry, process development scientists in the pharmaceutical industry, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel nucleoside analogs and antiviral or anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to pyrimidine metabolism and orotate metabolism pathways.
• Process Development: Employed in the scale-up and optimization of synthetic routes for complex organic molecules in fine chemical production.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and metabolic engineering.

Basic Information

Product Name	5-Methylorotic Acid
CAS No.	3993-73-5
Molecular Formula	C6H6N2O4
Molecular Weight	170.12 g/mol
Synonyms	5-Methylorotic Acid; 1,2,3,6-Tetrahydro-5-methyl-2,6-dioxo-4-pyrimidinecarboxylic Acid; 5-Methyl-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic Acid; 5-Methylorotate; NSC 52342; 5-Methyl-1H-pyrimidine-2,4,6-trione-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Methylorotic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.