Description

3-Chloroalanine is a versatile non-natural amino acid derivative that serves as a critical chiral building block in organic synthesis. Its value lies in the introduction of a reactive chloro group adjacent to the amino acid functionality, enabling a range of chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-lactam antibiotics, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics to study structure-activity relationships.
• Chemical Biology Probes: Serves as a precursor for creating activity-based probes and labeled compounds for metabolic studies.
• Ligand Synthesis: Intermediate in the preparation of chiral ligands for asymmetric catalysis.
• Academic & R&D: Fundamental research reagent in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	3-Chloroalanine
CAS No.	3981-36-0
Molecular Formula	C3H6ClNO2
Molecular Weight	123.54 g/mol
Synonyms	(S)-2-Amino-3-chloropropanoic acid; (S)-3-Chloroalanine; L-3-Chloroalanine; 3-Chloro-L-alanine; β-Chloro-L-alanine; 2-Amino-3-chloropropionic acid; Chloroalanine; NSC 85885
EINECS	Contact for details

Quality Control

Our 3-Chloroalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.