Description

N'-Formyl-L-Kynurenine is a key intermediate metabolite in the tryptophan degradation pathway, specifically in the kynurenine pathway. This compound is of significant interest in biochemical research for its role in immune regulation and neurological processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for studying metabolic disorders, neuroinflammation, and as a reference standard.

Application

• Biochemical Research: Critical intermediate for studying the kynurenine pathway and its implications in health and disease.
• Pharmaceutical Development: Used as a reference standard and building block in the research of novel therapeutics targeting immune modulation and neurological conditions.
• Metabolite Analysis: Serves as a calibration standard in analytical methods such as HPLC and LC-MS for quantifying tryptophan metabolites in biological samples.
• Enzymology Studies: Substrate for studying the activity and kinetics of enzymes like indoleamine 2,3-dioxygenase (IDO) and kynurenine formamidase.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the effects of kynurenine pathway metabolites on immune cell function and neuronal activity.

Basic Information

Product Name	N'-Formyl-L-Kynurenine
CAS No.	3978-11-8
Molecular Formula	C11H12N2O4
Molecular Weight	236.22 g/mol
Synonyms	L-Formylkynurenine; N(omega)-Formyl-L-kynurenine; 2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid; (S)-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid; N'-Formylkynurenine; Formylkynurenine; Kynurenine, N'-formyl-; Tryptophan metabolite
EINECS	Contact for details

Quality Control

Our N'-Formyl-L-Kynurenine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.