Description

(2Rs,3Rs)-2-Amino-3-(3,4-Dihydroxy-Phenyl)-3-Hydroxy-Propionic Acid is a high-purity, stereochemically defined amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a critical chiral building block for developing novel bioactive molecules, particularly in the synthesis of complex natural products and potential drug candidates. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptidomimetics, enzyme inhibitors, and other sophisticated chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and metabolic targets.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving tyrosine or catecholamine metabolism pathways.
• Peptide Synthesis: Acts as a specialized, non-proteinogenic amino acid for incorporating unique structural and functional motifs into synthetic peptides and peptidomimetics.
• Asymmetric Synthesis Catalyst Precursor: Employed in the development of chiral ligands and organocatalysts for stereoselective chemical transformations.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	(2Rs,3Rs)-2-Amino-3-(3,4-Dihydroxy-Phenyl)-3-Hydroxy-Propionic Acid
CAS No.	3916-18-5
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	(2R,3R)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid; (2R,3R)-β-3,4-Dihydroxyphenylserine; L-three-3,4-Dihydroxyphenylserine; Droxidopa impurity; L-DOPS related compound; (2R,3R)-DOPS; 3-Hydroxy-L-tyrosine; Erythro-3,4-dihydroxy-L-phenylserine
EINECS	Contact for details

Quality Control

Our (2Rs,3Rs)-2-Amino-3-(3,4-Dihydroxy-Phenyl)-3-Hydroxy-Propionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2R,3R)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.