Description

2',6'-Difluoroacetanilide is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those containing difluorophenyl motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and thermal stability.
• Organic Electronics: Employed in the research and development of organic semiconductors and charge-transport materials.
• Chemical Research: A versatile reagent for academic and industrial research in fluorination chemistry and cross-coupling reactions.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2',6'-Difluoroacetanilide
CAS No.	3896-29-5
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	N-(2,6-Difluorophenyl)acetamide; 2,6-Difluoroacetanilide; Acetamide, N-(2,6-difluorophenyl)-; 2,6-DFA; 2,6-Difluoro-N-acetylaniline; 1-Acetamido-2,6-difluorobenzene; 2',6'-Difluoracetanilid; N-Acetyl-2,6-difluoroaniline
EINECS	223-448-8

Quality Control

Our 2',6'-Difluoroacetanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 149 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.