Description

3,4-Difluoroaniline is a versatile aromatic amine building block characterized by its two fluorine substituents on the benzene ring. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its fluorine atoms impart unique electronic and metabolic stability properties. It is a critical intermediate for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries seeking to develop novel compounds with enhanced performance.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into high-performance polymers to enhance thermal stability, chemical resistance, and surface properties.
• Dyestuff & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-value applications.
• Cross-coupling Reactions: An important substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions for complex molecule assembly.

Basic Information

Product Name	3,4-Difluoroaniline
CAS No.	3863-11-4
Molecular Formula	C6H5F2N
Molecular Weight	129.11 g/mol
Synonyms	3,4-Difluorobenzenamine; 3,4-DFA; 1-Amino-3,4-difluorobenzene; Benzenamine, 3,4-difluoro-; 3,4-Difluoro-phenylamine; 3,4-Difluoroaniline (DFA); 3,4-Difluoroaminobenzene
EINECS	223-383-6

Quality Control

Our 3,4-Difluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Density (at 20°C)	~1.25 g/cm³
Boiling Point	~180-182 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.