Description

H-Nle-Ome Hcl is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of N-α-Boc-Norleucine. This compound serves as a crucial building block in peptide synthesis, offering controlled reactivity for the sequential assembly of complex peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers involved in developing novel therapeutic peptides and biochemical tools.

Application

• Peptide Synthesis: As a key intermediate for the controlled incorporation of norleucine residues into peptide sequences.
• Pharmaceutical Research: Used in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a reagent for modifying proteins or other biomolecules.
• Chemical Biology: Employed in the synthesis of peptide probes and tools for studying biological processes.
• Agrochemical Development: Potential use in the synthesis of bioactive peptide mimetics for crop protection.
• Academic Research: A standard reagent in university and institutional laboratories for organic and medicinal chemistry studies.

Basic Information

Product Name	H-Nle-Ome Hcl
CAS No.	3844-54-0
Molecular Formula	C8H18ClNO3
Molecular Weight	211.69 g/mol
Synonyms	Norleucine methyl ester hydrochloride; L-Norleucine methyl ester hydrochloride; H-Nle-OMe·HCl; (S)-2-Aminohexanoic acid methyl ester hydrochloride; Methyl L-norleucinate hydrochloride; Boc-Nle-OMe (precursor form); 2-Aminohexanoic acid methyl ester hydrochloride; 3844-54-0
EINECS	223-350-5

Quality Control

Our H-Nle-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.